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Clinical data Routes of administration    Smoked, Oral Legal status AU: S9 (Prohibited) CA: Schedule II DE: Anlage II (Authorized trade only, not prescriptible) US: Schedule I Identifiers IUPAC name[show] CAS Number 209414-07-3 PubChem CID 10382701 ChemSpider 8558143 Yes ChEMBL CHEMBL561013 Yes ECHA InfoCard    100.163.574 Chemical and physical data Formula    C24H23NO Molar mass    341.45 g/mol Solubility in water    hydrophobic, n/a mg/mL (20 °C) InChI[show] Yes (what is this?)  (verify) JWH018 is a full agonist of both the CB1 and CB2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB1 and 2.94 ± 2.65 nM at CB2. [3] JWH-018 has an EC50 of 102 nM for human CB1 receptors, and 133 nM for human CB2 receptors. [12] JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, suggesting potent cannabinoid-like activity. Buy jwh-018 online and get discreet packaging